Labor Day Sale! Up to 25% OFF Sitewide

Code: LABOR2026 | Terms

L-Serine Supplement

$ 19.95

L-Serine supports brain health and cell maintenance, helping you stay sharp and energized for daily challenges.
Buy More Save More
Purchase: Subscription

Description

L-Serine is a naturally occurring amino acid involved in the production of proteins, phospholipids, and sphingolipids that are important components of cells and nervous-system tissue. It also serves as a precursor to compounds including glycine and cysteine and plays a role in normal cellular metabolism.

L-Serine has been studied in human neurological research at a wide range of doses. In a six-month Phase I trial in patients with ALS, researchers evaluated doses ranging from 0.5 grams to 15 grams twice daily and found L-serine was generally well tolerated in the small study (Levine et al., 2017). Double Wood provides a more moderate 2,000 mg daily serving for general supplementation.

Soy-Free, Gluten-Free, Non-GMO, Vegan

Benefits
  • SUPPORT SEROTONIN LEVELS: L-Serine is an essentially amino acid that is vital to the production of both Tryptophan and Serotonin
  • SUPPORT COGNITIVE FUNCTION: L-Serine is vital to the health of brain proteins and nerve coverings which may help support overall cognitive function
  • 2,000 MG DAILY SERVING: Double Wood provides 2,000 mg of L-Serine per daily serving, with 180 capsules providing a 45-day supply.
  • ROOTED IN QUALITY: Manufactured and Tested in the USA from Globally Sourced Ingredients. Double Wood's L-Serine capsules are manufactured and tested for microbes and heavy metals right here in the USA.
  • WE BOTTLE WELLNESS: At Double Wood we provide pure, potent supplements that deliver exceptional value, all backed by careful sourcing and rigorous third-party testing.Common spellings include (L-Serine, L Serine, LSerine)

Directions & Dosage

For general use as a supplement, our recommended L-Serine dosage is 2000 mg per day. (4x 500 mg capsules.) L-Serine is water soluble and so does not need to be taken with food. It is often used in the evening, as it has a beneficial effect on sleep quality.

While we typically don’t recommend a dosage of over 6,000 mg per day there have been studies showing its safe use at dosages as high as 15,000 mg per day. We recommend avoiding doses this high as there is a much higher potential for side effects.

View Latest Test Results

Third-party tested for quality and purity

This production lot was tested for ingredient potency, capsule weight, disintegration, heavy metals, and microbial quality.

Test Claim or Limit Result
Potency
L-Serine 1800-2500 mg 1968 mg
Physical Testing
Capsule Weight 762-802 mg 782 mg
Disintegration NMT 30 Minutes Passed
Heavy Metals
Arsenic (As) ICP<10 µg/serving 0.048 µg/serving
Cadmium (Cd) ICP<4.1 µg/serving 0.005 µg/serving
Lead (Pb) ICP<0.5 µg/serving 0.080 µg/serving
Mercury (Hg) ICP<0.3 µg/serving <0.000 µg/serving
Microbial Testing
Total Plate Count <10,000 CFU/g <190 CFU/g
Total Yeast & Mold Count <1,000 CFU/g <19 CFU/g
E.Coli Absent Absent
Salmonella spp. Absent Absent
Staphylococcus aureus Absent Absent

Lot: 2522702Manufactured: 11/2025

Lab: Brand Nutraceuticals, Inc.

View Certificate of Analysis (PDF)

See the original Certificate of Analysis for complete testing details, methods, and laboratory documentation.
View Certificate of Analysis View Third Party Test Results
Identity, potency, and contaminants verified per batch Identity, potency, and contaminants verified per batch
Manufactured in an FDA-registered cGMP facility Manufactured in an FDA-registered cGMP facility
Manufactured in the USA from Gloabally Sourced Materials Manufactured in the USA from Gloabally Sourced Materials

Benefits

  • Support Serotonin Levels - L Serine is an essentially amino acid that is vital to the production of both Tryptophan and Serotonin
  • Support Cognitive Function - L Serine is vital to the health of brain proteins and nerve coverings which help support overall cognitive function
  • Whopping 2,000 mg Serving Size - Double Wood provides 180 capsules (45 days of the 2,000mg serving size used in the recent studies showing L Serine may support brain health and cognitive function
  • Vegan, Non Gmo, and Gluten Free; Our L Serine capsules are vegan friendly, Non Gmo, and gluten free - Our product is also Manufactured in the USA from Globally Sourced Ingredients
Benefits

L-Serine

A non-essential amino acid important for phospholipids. As a dietary nutrient, it is found in foods and may complement an everyday nutrition routine. It is commonly chosen to supports brain and nervous system function.

L-Serine

What Customers Are Saying

Reviews

"Reputation of product and overall delivery and ordering experience has always been a good experience."

Jacqueline P.

"Always fast shipping and great selection no matter what you’re looking for."

Aaron B.

"Double Wood is always my go-to for supplements. Great, effective, clean products and always at a reasonable price."

Jan W.

See All Reviews
Reviews
Supplement Facts

Pairs well with

Powerful alone, stronger together. L-Serine Supplement delivers targeted support on its own, but combining it with complementary ingredients can help create a more holistic and balanced approach to wellness.

  • Magnesium Glycinate Supplement

    Magnesium Glycinate promotes relaxation and supports overall wellness, making it a great addition to your daily routine.

  • Daily Fruit & Veggie Supplement

    Daily Fruit and Vegetables offers a powerhouse blend of 23 veggies and 26 fruits, making it easy to boost your overall nutrition.

Frequently Asked Questions

What are the benefits of L-serine?

L-serine is an amino acid involved in protein synthesis, one-carbon metabolism, and the production of phospholipids and sphingolipids used in cell membranes. It also serves as a precursor to glycine, cysteine, and other compounds involved in brain and cellular function. Double Wood provides 2,000 mg of L-serine per four-capsule serving.

Does L-serine help with sleep?

L-serine may support sleep quality for some people. In a randomized crossover study, adults who were dissatisfied with their sleep took 3 grams of L-serine 30 minutes before bed and reported improvements in sleep initiation and maintenance compared with placebo. Double Wood provides a 2,000 mg serving and may be taken in the evening, although individual results can vary.

What foods are high in L-serine?

L-serine occurs naturally in protein-containing foods such as soybeans and tofu, eggs, dairy products, meat, fish, nuts, and seeds. The body can also produce L-serine, although needs may vary by individual circumstances. Supplementation provides a measured amount without requiring someone to calculate the L-serine content of individual foods.

What are the side effects of L-serine?

L-serine is generally well tolerated, but higher amounts may cause mild digestive effects such as nausea, stomach discomfort, or diarrhea. Double Wood recommends 2,000 mg daily and does not generally recommend exceeding 6,000 mg per day. Higher doses studied for medical purposes should not be used without guidance from a qualified healthcare professional.

Overall rating: 4.716981 / 5 from 53 reviews.

AI Generated Review Summary

L-Serine Supplement is praised for its fair pricing and excellent value for money, making it a cost-effective choice for those seeking to support neuron health and amino acid production.

Summary topics

  • Price (15%): A significant number of customers stated that the product offers great quality at a very fair price.
  • Value for Money (15%): A significant number of customers remarked that the product offers great value and good value for money.

Review topics: [size, quality, value, price, sleep, supplement, sleep aid, use].

Review highlights

  • "Great quality at super price." — Anonymous
  • "Good value for this product, I would purchase their L-Serine again" — Anonymous
  • "Very beneficial and good value." — Debbie

Reviews

I think it helps me !

"I think l-serine helps me to think better and to sleep better. I’ve been taking it for years"

— Glenda B. (5/5)

Best Ever!!!

"So happy with this amino acid. I was about to go on LDN. Now I am so happy with the results of this product I'm just sticking with my 2000 milligrams and satisfied. My fatigue is sooo much better also memory, mood,and recall is better than in years. A TRUE game changer for me!!!!!"

— Mary L. (5/5)

I’m

"I’ve”left it off at times . . enough to know that L- Serine DOES help with memory!!!"

— Glenda B. (5/5)

L-Serine

"So far like the product."

— Helen P. (4/5)

L-Serine

"Good quality"

— Edward F. (5/5)

Helps my memory!

"I have been taking this supplement for a few months now and feel that I struggle less to recall things. It's been quite an improvement for me!"

— Anne D. (5/5)

L-Serine

"I take these for brain health, Alzheimer’s prevention. I won’t know if they are effective for years. No way to measure short term efficacy."

— CAROLYN H. (5/5)

Very good product - I

"Very good product - I take it at bedtime. Helps with sleep."

— Craig (5/5)

This product has reduced tremors

"This product has reduced tremors in my husband's hands. Very beneficial and good value. Thanks"

— Debbie (5/5)

Feeling better.

"Feeling better."

— Anonymous (4/5)

Q&A

L-Serine Supplement

From

$ 19.95

Primary Benefit

Brain Health

Other Benefits

Sleep

Product Form

Capsule
View product
Double Wood Supplements BBB Business Review